4-[3-(4-fluorophenyl)-1H-pyrazol-4-yl]pyridine

This compound is a synthetic small molecule belonging to the phenylpyrazole class, characterized by a pyrazole ring substituted with a 4-fluorophenyl group and linked to a pyridine ring. It acts as an experimental inhibitor of mitogen-activated protein kinase 14 (MAPK14), also known as p38 alpha MAP kinase, which is involved in cellular responses to stress and inflammation. The compound has not been approved for clinical use and has no reported indications or completed clinical trials beyond preclinical research. Its primary mechanism of action is inhibition of MAPK14, with an IC50 value of approximately 67 nM[1][3][5].

Other names

4-[3-(4-fluorophenyl)-1H-pyrazol-4-yl]pyridine4-[5-(4-fluorophenyl)-1H-pyrazol-4-yl]pyridine